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Eric Topol

@EricTopol830k followers

physician-scientist, author of SUPER AGERS and Ground Truths:

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1Jan 13, '23Our comprehensive review of #LongCovid has just been published Phenomenal work by @ahandvanish @LisaAMcCorkell @juliamv @NatureRevMicro45.3×5.7M13k5.9k4.5k
2Aug 13, '23It is despicable that the Covid vaccine manufacturers are going to charge more than $110/dose for the new XBB.1.5 boosters when available in mid-September. The US government previo17.4×2.2M10k3.2k329
3May 27, '25A new cover for SUPER AGERS after making the NYT bestseller list. Thanks to you for making it the #1 ranked new non-fiction book on Amazon.13.2×1.6M2.3k5031.5k
4Jun 27, '23An inhaled Covid vaccine booster was more than 5-fold effective for inducing neutralizing antibodies at 28-days, and more durable at 1-year, than shots, vs Omicron BA.5 in a random12.7×1.6M6.3k1.6k631
5Jan 4, '24My oped on the JN.1 variant and the 2nd biggest US wave of infections (after Omicron) since the pandemic began @latimes @latimesopinion #LongCovid12.3×1.5M6.2k2.7k1.1k
6Mar 24, '25Of >105,000 participants with 30-year follow-up, only 9.3% achieved healthy aging (age 70, w/o any chronic diseases). Their diet was significantly associated with this outcome🧵9.1×1.1M6.4k1.4k6.2k
7Apr 10, '23This is big, folks. The @WhiteHouse is supporting next generation—nasal and variant-proof Covid vaccines —and therapies with a $5 billion program by @ddiamond Thanks to the relentl8.9×1.1M6.4k1.7k445
8Nov 28, '20This will go down in history as one of science and medical research's greatest achievements. Perhaps the most impressive. I put together a preliminary timeline of some key mileston8.8×035k9.8k2.7k
9Jul 31, '21Pretty damn impressive Thanks Darren Lu @Reddit6.7×029k8.9k1.3k
10Jan 9, '23The virus is talking. We're not listening6.1×768k5.1k2.1k455
11Sep 25, '24Two doses of a Covid nasal vaccine spray led to >50-fold increase in spike-specific secretory IgA antibodies against 10 strains of #SARSCoV2, indicative of potent mucosal immunity 6.0×752k4.9k1.2k1.3k
12Aug 9, '23More than 3 years in, with tens of millions of people still suffering, this is the comprehensive list of validated treatments for #LongCovid, as established through rigorous, rando5.6×699k4.8k1.6k376
13Mar 12, '22The next wave in Europe has begun5.4×016k7.4k851
14Mar 30, '22Ivermectin: the largest randomized, double-blind trial yet conducted, with early treatment, indicates there is no difference compared with placebo. It doesn't work. Period. just pu5.4×017k6k1.1k
15Mar 28, '21You don’t get 3+ million shots a day without tens of thousands of volunteers. A salute to them. A sign of unity for a common, vital purpose4.6×029k2.6k19
16Oct 18, '20Almost the whole country is in the "Uncontrolled Spread" category 1/4.5×013k6.8k509
17Oct 7, '20The patient had a whopping (8g) dose of a #SARSCoV2 neutralizing IgG antibody cocktail. Then they detected antibodies. You must be kidding me, Dr. Conley?4.3×020k4.7k342
18Aug 1, '21Today, Canada surpassed Israel for fully vaccinated, a very high bar. Congratulations 🇨🇦4.2×023k3.1k147
19Apr 15, '21Airborne it is. 🦠 The 10 streams of overwhelming evidence @TheLancet by @trishgreenhalgh @kprather88 @Rschooley @zeynep @jljcolorado @dfisman a 5-★ succinct summary4.0×012k6.5k1.5k
20Feb 27, '21The way to end the week: best US vaccination day 2.2 million, a new record3.8×023k2.4k43
21Dec 27, '20One per thousand Americans have now died from covid-19. How does that compare with 12 other select countries with >20 million population?3.4×011k5.3k599
22Jan 2, '25A nasal spray prevented 80% of Covid infections; ~300,000 people in China have received it. [called SA55, a broad spectrum monoclonal antibody, developed by @yunlong_cao and collea2.9×357k6.4k1.7k2.1k
23Dec 28, '21The data that supports the new @CDCgov 5 day isolation period without a negative test2.8×013k3.1k237
24Apr 8, '21Over 110 million Americans have now had a taste of universal health care. Free vaccines.2.7×016k2k33
25May 7, '20How can a country that has required you to take your shoes off at airport security for a 2001 foiled attempt without a single person hurt ...... be the same one that has no systema2.7×012k3.5k140
26Dec 12, '20Covid in context by @Rob_Rogers2.6×011k3.5k281
27Jan 5, '21If we wanted to get serious vs B.1.1.7 —get N95/K95 masks to all and enforce their use —get rapid home testing big supply to each household for daily use —amp up digital, mobility,2.6×012k3.1k241
28Jan 10, '22What happens when one of the best vaccinated (90% total population) countries in the world gets Omicron? 🇵🇹2.6×011k2.9k465
29May 22, '20Just published @TheLancet The largest study of hydroxychloroquine shows a significant increase in death (~35%) and >2-fold increase of serious heart arrhythmias. ~96,000 patient2.6×06.6k4.5k421
30Oct 18, '21Fixed that for you @johnrobertsFox2.5×013k2.5k154
31Jul 23, '22Anyone who thinks BA.5 is just another variant isn't paying attention >200,000 new cases yesterday. Vertical.2.5×09.1k3.6k385
32Dec 4, '21About 5 million children age 5-11 now vaccinated with their first dose (nearly ~1 million with 2nd dose) and I've yet to see a case of myocarditis reported 👍2.3×011k2.3k218
33May 12, '22This week @TheLancet's cover2.3×09.5k3.4k145
34Feb 6, '21It keeps getting better: 2.1 million vaccines administered in the USA today! 👏2.3×012k1.8k64
35Oct 5, '20Fixed this for you, @realDonaldTrump2.2×010k2.9k103
37Aug 22, '21The mRNA vaccine story was by no means fast. Both it and lipid nanoparticles for its delivery took several decades2.1×07.4k2.9k1.1k
38Jan 24, '22How to reduce your chance of dying from Covid by 99%? Get vaccinated and a booster. One of the most impressive graphs I've seen for the impact of vaccination in the US pandemic (th2.1×07.1k3.2k500
39Nov 21, '21That over 3 million children age 5-11 in the US have been vaccinated without a reported case of myocarditis so far is encouraging2.1×010k2.2k163
40Oct 8, '17Your. Medical. Data.2.1×07.2k3k424
41Apr 3, '21Who would ever have thought that the same country that couldn't even get a covid test working and scalable for 2 months could vaccinate more than 4 million people in a day? Quite a2.1×012k1.3k42
42Feb 3, '21"The evidence is now clear. #SARSCoV2 is transmitted predominantly through the air — by people talking and breathing out large droplets and small particles called aerosols. Catchin2.1×06.6k3.5k444
43Jul 18, '22Epstein-Barr virus is the leading cause of multiple sclerosis Summary of one of the most important advances in life science this year @ScienceMagazine2.1×07.8k2.4k1.1k
44Mar 17, '20What will go down as the biggest breakdown in the US response to #COVID19 is the lack of test kits. South Korea and the US had their 1st patients on Jan 20 and Jan 21, respectively2.1×06.2k3.6k366
45Jul 8, '22This is our @CDCgov X No warning on BA.5 X Still says 2 vaccine doses ="fully vaccinated" X Says 5 days is all that's needed for isolation when 5 days is the median length of infec2.0×07.5k2.9k494
46Mar 16, '22When South Korea, a model country for the pandemic, has >400,000 new cases in a day, leading the world per capita, you take notice. Tests 4X the US with <1/6th the population2.0×07.5k2.9k401
47Dec 10, '21There's been a lot of new data for Omicron in the last day, much still preliminary, but here's my summary of the good and bad2.0×07.2k2.8k601
48Jan 2, '22It's pretty impressive that vaccines directed to the ancestral strain spike from 2 years ago, w/ the virus that's evolved thru >290 million confirmed cases, and now to the hyper2.0×010k1.7k206
49May 5, '21Vaccines don't just work. They work across all the variants, providing protection from illness, hospitalizations, and deaths. Summary including today's multiple updates. (and we're2.0×08.1k2.8k287
50Mar 11, '22Here we go again @OurWorldInData1.9×06.2k2.5k360
51Dec 5, '20Diagnosing why the US has so blatantly failed to respond to #COVID19 by 2 tweets1.9×09.9k1.7k98
52Dec 22, '21You know it's a good day in the pandemic when: —The 1st anti-Covid pill is cleared —More indications that Omicron is associated with less severe illness and tends to come down from1.9×09.8k1.7k162
53Mar 7, '22Just published @nature The impact of #Covid on the brain: the 1st longitudinal imaging study before and after infection, with controls Reduction of grey matter, brain size, cogniti1.9×04.9k2.9k931
54Aug 26, '21Just published @ScienceMagazine A phenomenal, tour de force review of aerosol transmission of respiratory viruses, from the experts. #COVIDisAirborne w/ @ScienceVisuals1.8×05.4k2.5k1.3k
55Aug 13, '21The Delta waves in the US and Canada, a striking contrast. Fully vaccinated of total population: Canada 64% US 50%1.8×06.4k2.6k211
56Oct 7, '21Deleted.1.7×08.9k1.2k129
57Aug 11, '21There needs to be truth-telling about the reduced protection of mRNA vaccines vs symptomatic Delta infections. It was 95% pre-Delta. Many are claiming it's still ~80%. It isn't. 501.7×05.1k2.1k736
58Apr 23, '21We now have solid evidence that there are vaccines that protect against all variants of concern: ✓ B.1.351 (S Africa) ✓ P.1 (Brazil) ✓ B.1.1.7 (UK) ✓ B.1.526 (NY) ✓ B.1.429 (CA)1.7×08.1k1.8k226
59Aug 1, '21All Delta here in July. The 8:1 odds are pretty good.1.6×06.9k2.1k294
60Jul 8, '22Today's @washingtonpost editorial on the BA.5 variant1.6×05.3k2.4k640
61Dec 5, '2010 countries, 1 outlier1.6×06k2k285
62Jan 12, '22I get a lot of questions about "my team" who helps with my twitter posts. Let me make it clear. The "team" is me. >12 years, >40K posts, most since the pandemic began. Every 1.6×010k34177
63Dec 1, '21Fully vaccinated = 3 shots.1.5×06.5k96473
64Oct 23, '21What happens when teens are not vaccinated1.5×05.5k2.2k249
65Dec 8, '21Just published @NEJM A striking 90% reduction in death for booster shots (vs not receiving the 3rd shot) among over 840,000 people, age 50 or older1.5×05.4k2.1k353
66Aug 21, '22I wrote about where we stand with #LongCovid after a cluster of new studies @latimes1.5×05.1k1.7k937
67Aug 23, '20Today's "breakthrough" announcement is unlikely to be any breakthrough. 1. Convalescent plasma has no randomized trials. It contains many antibodies that have no neutralizing effec1.5×05.4k2.1k227
68Apr 19, '22At the airport, with no interest for a visit with BA.2 or serving as an asymptomatic vector. Tight fit KN 94 underneath1.5×08.8k54777
69Nov 24, '21Don't tell me "cases are irrelevant" That means you don't understand: —Cases beget cases. People getting sick. Surges. —Cases beget #LongCovid —Cases beget hospitalizations & d1.5×06.4k1.7k201
70Mar 17, '22Hello 🇺🇸 You just got over a wave of the most transmissible #SARSCoV2 variant the world has seen, with the highest level of hospitalizations in the pandemic. Now you are facing a1.4×05.5k1.9k202
71Aug 10, '21Debunking the myth that vaccination promotes mutations. Being fully vaccinated actually suppresses them1.4×05k1.8k437
72Jun 13, '22"We estimated that a single-payer universal healthcare system would have saved 212,000 lives in 2020 alone. We also calculated that US$105.6 billion of medical expenses associated 1.4×04.9k2.1k309
73May 30, '21The 🦠 continues to evolve, gets more fit, but has yet to outsmart the vaccines that humans made to block it. If only more humans could outsmart the virus by getting vaccinated. An1.4×06.9k1.5k53
74Oct 12, '20Our covid times :-)1.4×05.3k2.2k125
75Feb 24, '21Summary of the 5 Phase 3 vaccine trials. One theme: 100% protection from death and hospitalizations That is impressive!1.3×05.2k1.8k262
76May 2, '21We are fortunate that vaccines induce such a strong immune response and provide protection from all of the virus variants that have evolved to date1.3×05.6k1.6k272
77Aug 15, '22The use of high-quality masks (like N95/KN95 respirators) by patients, compared with surgical masks, substantially reduced Covid infections among nearly 4,000 health care workers @1.3×05k1.6k505
78Sep 19, '22Wish this was true. What's over is @POTUS's and our government's will to get ahead of it, with magical thinking on the new bivalent boosters. Ignores #LongCovid, inevitability of n1.3×05.7k1.6k200
79Apr 18, '20New Zealand knows how to do it!🇳🇿1.3×05.3k1.7k108
80Jun 5, '21As of today, 3 countries have reached ≥ 60% of their total population with their 1st vaccination dose. And Canada became the world's leader1.3×05.5k1.3k60
81Feb 21, '21The good news is that South Africa is back to its pre-B.1.351 baseline in covid cases. There's no proof this variant is more infectious. Its immune evasion is enough to explain how1.2×05.3k1.4k157
82Feb 21, '21From incalculable to 5X incalculable. Unfathomable. Mostly preventable.1.2×05.2k1.6k136
83Oct 24, '21Japan fully contained after its worst surge related to Delta, 💉 quickly rose to now 78% of total population w/ ≥ 1 dose, test positivity went from 25% to 1%, cases >23,000 to &1.2×05.1k1.4k129
84Nov 29, '21Besides South Africa and Botswana, 12 countries have now reported confirmed cases of Omicron. And many more will do so in the next few days. Had it not been for the sequencing and 1.2×06.1k1.1k50
85May 27, '22American exceptionalism The United States comprises 4% of the world's population ✓ 16% of the world's Covid confirmed deaths ✓ 40% of world's guns ✓ Only industrialized nation in t1.2×05k1.4k201
86Nov 15, '20Fixed this for you, @realDonaldTrump1.2×06.8k72823
87Apr 17, '22Something to celebrate. The lowest Covid death rate in over 2 years @OurWorldInData1.1×05.8k1.1k72
88Sep 3, '21How to lose public confidence? 1. Announce a booster program on Sept 20 for all at 8 months post-vaccine 2. Change it to 6 months, then 5 months, then back to 8 3. Lack of agreemen1.1×05.2k1.1k180
89Aug 26, '21How to manage a Delta wave? Iceland. 78% total population fully vaccinated. A+1.1×05.2k1.3k143
90Dec 6, '20How Rudy Giuliani didn't get covid until now is the more interesting question. They're likely getting a #SARSCoV2 monoclonal antibody ready for infusion. This treatment an affinity1.1×05.4k1.1k65
91Jun 24, '21Leave it to Canada to show how to vaccinate their population. First, despite a late start, they exceeded the % 1st dose ceiling set by Israel. Now on a tear for 2nd dose, and movin1.1×04.9k1.2k85
92Mar 13, '21NEW RECORD and a big jump from the one set yesterday 4.58 vaccine doses in the US today! And a new Y-axis.1.1×04.9k1k35
93Feb 1, '22Our covid times by @MatttDavies1.1×05.2k1.2k99
94Apr 1, '21Not exactly. You can be vaccinated and carry the virus (carrier). But if the viral load is so low you can't transmit (not a transmitter) spread is blocked and we move onto the pand1.1×05k1.2k182
95Jul 17, '21Today's the day that Canada exceeded the US for fully vaccinated. Congratulations 🇨🇦 And 15% points ahead in 1st dose. Your belief in the evidence and support of the science is a1.1×04.8k1.1k54
96Jun 2, '21Zero. First time. Congratulations UK. Saluting the incredible hard work and solidarity that got you here 🇬🇧 #VaccinesWork1.0×05.5k92927
97Nov 10, '20That one, @realDonaldTrump, required quite a bit of editing to get to the truth1.0×05.4k85258
98May 12, '21We're about to hit the lowest death rate in the US for the pandemic0.9×05k77946
99Mar 12, '21Over 2.9 million vaccines today. The new record! Blew by 100 million total given. 👏👏0.9×04.8k88318
100Apr 2, '21What a good Friday! First 4.0M vaccine day in the US0.9×05.3k58516
101Oct 26, '20Interrupting covid news for some good news. A new granddaughter. Who has a big sister and brother. Our social bubble here in San Diego.0.8×05k445

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